Published by Industrial Water Research, research@tallyfox.com in Academic
Category: Academic
Following on from the use of powerful oxidising agents being (relatively) indescriminate in their disruption of cells to reneder them non-viable. My feeling is that "clean" oxidants eg ozone, which don't leave halogenated organics behind, may have an increasing role to play in both disinfection and the avoidance of Anti Microbial Resistance (AMR).
Published by Peter Barratt, Research & Development Director at Oxi-Tech Solutions Limited
"Resistance" is futile for oxidizers: one cannot develop a resistance to bullets and bombs. Ozone is indeed a great oxidant, like all oxidizers it has pro's and con's. it's primary con's include bromate formation, elevated corrosion rates, and insolubility above 94 DegF.
Published by Chris Baron
Thanks Chris. I couldn't agree more!
Published by Peter Barratt, Research & Development Director at Oxi-Tech Solutions Limited
Since the previous answers were technical, let's get a little descriptive: oxidizing biocides are like machine-guns or bazookas. They indiscriminately lay waste to all in their path.
Published by Chris Baron
Oxidizing biocides take in electrons. Mode of action in case of chlorine dioxide and Ozone is that they rupture the cell wall and then burst the nucleus and not leaving any microorganisms behind, thus developing no immunity or mutations of the bugs rendering the biocide effective.
Published by Chetan Shukla, Clean Environmental Technologies Pvt. Ltd. - Director
Since the active components of oxidizing biocides are acidic in nature (with the notable exception of hydrogen peroxide), it is no surprise at all that the system pH plays a role in biocide effectiveness.
Published by James Stewart
Its important to note that oxidizing biocides are consumed in a somewhat quantitive relationship with the target organism. The common term is "demand" which basically is the differential between the amount of biocide added and confirmed (tested) residual assuming adequate contact and reaction time. However, the by-products of the reaction commonly referred to as "disinfection by-products" (DBP) continue to have diminished biocidal properties.
Published by Tom Armon
Both Clive's and John's answers are correct, John has simplified it. To put it plainly, as one of my mentors used to say, they simply burn the cell walls.
Published by Arthur Matossian
Oxidizers are primarily acids i.e. HOCl, HCl, HOBr, HBr etc. The outer cell wall is anionic , the acid reacts and burns a hole in the cell wall causing the loss of osmonic pressure
Published by John Steel
Removal of electrons from target molecules, i.e. destruction of bio molecules, starting from cell walls.
Published by Clive Ling, Technical Consultant at Nalco Water, an Ecolab Company